ERCC5 Antibody
Product Specifications
Background
Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. [provided by RefSeq].
NCBI Gene ID
2073
Swiss Prot
P28715
Accession Number
P28715
Host
Rabbit
Reactivity
Human
Immunogen
This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human ERCC5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-501
Calculated Molecular Weight
133 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ERCC5
NCBI Official Name
DNA repair protein complementing XP-G cells
NCBI Organism
Homo sapiens
Background Reference 01
Figl, A., et al. Mutat. Res. 702 (1) :8-16 (2010)
Background Reference 02
Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
Background Reference 03
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 04
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Other Product Names
DNA repair protein complementing XP-G cells, 31--, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein, ERCC5, ERCM2, XPG, XPGC
Tested Applications
WB
Protein ID
205371791
Physical Properties
Liquid
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