ERCC5 Antibody

Product Specifications

Background

Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. [provided by RefSeq].

NCBI Gene ID

2073

Swiss Prot

P28715

Accession Number

P28715

Host

Rabbit

Reactivity

Human

Immunogen

This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human ERCC5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

133 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ERCC5

NCBI Official Name

DNA repair protein complementing XP-G cells

NCBI Organism

Homo sapiens

Background Reference 01

Figl, A., et al. Mutat. Res. 702 (1) :8-16 (2010)

Background Reference 02

Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :

Background Reference 03

Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)

Background Reference 04

Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :

Other Product Names

DNA repair protein complementing XP-G cells, 31--, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein, ERCC5, ERCM2, XPG, XPGC