ADCY9 Antibody

Product Specifications

Background

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.

NCBI Gene ID

115

Swiss Prot

O60503

Accession Number

O60503

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ADCY9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1295-1323 amino acids from the C-terminal region of human ADCY9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

151 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ADCY9

NCBI Official Name

Adenylate cyclase type 9

NCBI Organism

Homo sapiens

Background Reference 01

Wojcik, C., et al. Am. J. Med. Genet.152A (2), 479-483 (2010) :

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Tantisira, K.G., et al. Hum. Mol. Genet. 14 (12) :1671-1677 (2005)

Background Reference 04

Cumbay, M.G., et al. J. Pharmacol. Exp. Ther. 310 (1) :108-115 (2004)

Other Product Names

Adenylate cyclase type 9, ATP pyrophosphate-lyase 9, Adenylate cyclase type IX, Adenylyl cyclase 9, ADCY9, KIAA0520

Tested Applications

Physical Properties

Liquid

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