AGFG2 Antibody

Product Specifications

Background

This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. The 3' UTR of this gene contains an insulin receptor substrate 3-like pseudogene.

NCBI Gene ID

3268

Swiss Prot

O95081

Accession Number

O95081

Host

Rabbit

Reactivity

Human

Immunogen

This AGFG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human AGFG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AGFG2

NCBI Official Name

Arf-GAP domain and FG repeat-containing protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Doria, M., et al. J. Cell Biol. 147 (7) :1379-1384 (1999)

Background Reference 02

Glockner, G., et al. Genome Res. 8 (10) :1060-1073 (1998)

Background Reference 03

Salcini, A.E., et al. Genes Dev. 11 (17) :2239-2249 (1997)

Background Reference 04

Wong, W.T., et al. Proc. Natl. Acad. Sci. U.S.A. 92 (21) :9530-9534 (1995)

Other Product Names

Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain-binding protein related, RAB-R, AGFG2, HRBL, RABR