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CALCRL Antibody

Product Specifications

Background

Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity) . The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

NCBI Gene ID

10203

Swiss Prot

Q16602

Accession Number

Q16602

Host

Rabbit

Reactivity

Human

Immunogen

This CALCRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-367 amino acids from the Central region of human CALCRL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-491

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CALCRL

NCBI Official Name

Calcitonin gene-related peptide type 1 receptor

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Kuwasako, K., et al. Biochem. Biophys. Res. Commun. 392 (3) :380-385 (2010)

Background Reference 03

Chang, C.L., et al. J. Biol. Chem. 285 (2) :1075-1080 (2010)

Background Reference 04

Barwell, J., et al. Peptides 31 (1) :170-176 (2010)

Other Product Names

Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor, CALCRL, CGRPR

Tested Applications

WB

Protein ID

226693507

Physical Properties

Liquid

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