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NEO1 Antibody

Product Specifications

Background

This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

NCBI Gene ID

4756

Swiss Prot

Q92859

Accession Number

Q92859

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-685 amino acids from the Central region of human NEO1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

160 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NEO1

NCBI Official Name

Neogenin

NCBI Organism

Homo sapiens

Background Reference 01

Bradford, D., et al. J. Comp. Neurol. 518 (16) :3237-3253 (2010)

Background Reference 02

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 03

Zhang, A.S., et al. J. Biol. Chem. 284 (34) :22580-22589 (2009)

Background Reference 04

Fujita, Y., et al. Cell Death Differ. 15 (10) :1593-1608 (2008)

Other Product Names

Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN

Tested Applications

WB

Protein ID

116242676

Physical Properties

Liquid

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