SIX6 Antibody

Product Specifications

Background

The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2) .

NCBI Gene ID

4990

Swiss Prot

O95475

Accession Number

O95475

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SIX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human SIX6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SIX6

NCBI Official Name

Homeobox protein SIX6

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, X., et al. Mol. Vis. 15, 2911-2918 (2009) :

Background Reference 02

Ou, Z., et al. Am. J. Med. Genet.146A (19), 2480-2489 (2008) :

Background Reference 03

Hu, S., et al. Biochemistry 47 (11) :3586-3594 (2008)

Background Reference 04

Aijaz, S., et al. Invest. Ophthalmol. Vis. Sci. 45 (11) :3871-3876 (2004)

Other Product Names

Homeobox protein SIX6, Homeodomain protein OPTX2, Optic homeobox 2, Sine oculis homeobox homolog 6, SIX6, OPTX2, SIX9

Tested Applications

Physical Properties

Liquid

Curated Selection

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