TBR1 Antibody
Product Specifications
Background
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq].
NCBI Gene ID
10716
Swiss Prot
Q16650
Accession Number
Q16650
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human TBR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TBR1
NCBI Official Name
T-box brain protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)
Background Reference 02
Stefanovska, A.M., et al. Cancer Res. 61 (22) :8351-8352 (2001)
Background Reference 03
Hsueh, Y.P., et al. Nature 404 (6775) :298-302 (2000)
Background Reference 04
Bulfone, A., et al. Neuron 15 (1) :63-78 (1995)
Other Product Names
T-box brain protein 1, T-brain-1, TBR-1, TES-56, TBR1
Tested Applications
WB
Protein ID
2501122
Physical Properties
Liquid
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