UAP1 Antibody

Product Specifications

Background

UAP1 converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

NCBI Gene ID

6675

Swiss Prot

Q16222

Accession Number

Q16222

Host

Rabbit

Reactivity

Human

Immunogen

This UAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human UAP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UAP1

NCBI Official Name

UDP-N-acetylhexosamine pyrophosphorylase

NCBI Organism

Homo sapiens

Background Reference 01

Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

Background Reference 02

Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

Background Reference 03

Peneff, C., et al. EMBO J. 20 (22) :6191-6202 (2001)

Background Reference 04

Wang-Gillam, A., et al. J. Biol. Chem. 273 (42) :27055-27057 (1998)

Other Product Names

UDP-N-acetylhexosamine pyrophosphorylase, Antigen X, AGX, Sperm-associated antigen 2, UDP-N-acetylgalactosamine pyrophosphorylase, AGX-1, UDP-N-acetylglucosamine pyrophosphorylase, AGX-2, UAP1, SPAG2