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TCERG1 Antibody

Product Specifications

Background

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

NCBI Gene ID

10915

Swiss Prot

O14776

Accession Number

O14776

Host

Rabbit

Reactivity

Human

Immunogen

This TCERG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 991-1020 amino acids from the C-terminal region of human TCERG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TCERG1

NCBI Official Name

Transcription elongation regulator 1

NCBI Organism

Homo sapiens

Background Reference 01

Sanchez-Alvarez, M., et al. J. Biol. Chem. 285 (20) :15220-15233 (2010)

Background Reference 02

Koskinen, L.L., et al. Tissue Antigens 74 (5) :408-416 (2009)

Background Reference 03

Murphy, J.M., et al. J. Mol. Biol. 393 (2) :409-424 (2009)

Background Reference 04

Lu, M., et al. J. Mol. Biol. 393 (2) :397-408 (2009)

Other Product Names

Transcription elongation regulator 1, TATA box-binding protein-associated factor 2S, Transcription factor CA150, TCERG1, CA150, TAF2S

Tested Applications

WB

Physical Properties

Liquid

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