NHEDC2 Antibody

Product Specifications

Background

Sodium hydrogen antiporters, such as NHEDC2, convert the proton motive force established by the respiratory chain or the F1F0 mitochondrial ATPase into sodium gradients that drive other energy-requiring processes, transduce environmental signals into cell responses, or function in drug efflux (Xiang et al., 2007 [PubMed 18000046]) .

NCBI Gene ID

133308

Swiss Prot

Q86UD5

Accession Number

Q86UD5

Host

Rabbit

Reactivity

Human

Immunogen

This NHEDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human NHEDC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SLC9B2

NCBI Official Name

Mitochondrial sodium/hydrogen exchanger 9B2

NCBI Organism

Homo sapiens

Background Reference 01

Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)

Background Reference 02

Schushan, M., et al. J. Mol. Biol. 396 (5) :1181-1196 (2010)

Background Reference 03

Fuster, D.G., et al. J. Am. Soc. Nephrol. 19 (8) :1547-1556 (2008)

Background Reference 04

Battaglino, R.A., et al. Bone 42 (1) :180-192 (2008)

Other Product Names

Mitochondrial sodium/hydrogen exchanger 9B2, Mitochondrial Na (+) /H (+) exchanger NHA2, Na (+) /H (+) exchanger-like domain-containing protein 2, NHE domain-containing protein 2, Sodium/hydrogen exchanger-like domain-containing protein 2, Solute carrier family 9 subfamily B member 2, SLC9B2, NHA2, NHEDC2