NFKBIL2 Antibody
Product Specifications
Background
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
NCBI Gene ID
4796
Swiss Prot
Q96HA7
Accession Number
Q96HA7
Host
Rabbit
Reactivity
Human
Immunogen
This NFKBIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human NFKBIL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-419
Calculated Molecular Weight
151 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TONSL
NCBI Official Name
Tonsoku-like protein
NCBI Organism
Homo sapiens
Background Reference 01
Wang, Y., et al. J. Hum. Genet. 55 (8) :490-494 (2010)
Background Reference 02
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 03
Norman, D.A., et al. Ann. Hum. Genet. 64 (PT 1), 15-23 (2000) :
Background Reference 04
Ray, P., et al. J. Biol. Chem. 270 (18) :10680-10685 (1995)
Other Product Names
Tonsoku-like protein, Inhibitor of kappa B-related protein, I-kappa-B-related protein, IkappaBR, NF-kappa-B inhibitor-like protein 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2, TONSL, IKBR, NFKBIL2
Tested Applications
WB
Protein ID
182662416
Physical Properties
Liquid
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