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GJC3 Antibody

Product Specifications

Background

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.

NCBI Gene ID

349149

Swiss Prot

Q8NFK1

Accession Number

Q8NFK1

Host

Rabbit

Reactivity

Human

Immunogen

This GJC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-278 amino acids from the C-terminal region of human GJC3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GJC3

NCBI Official Name

Gap junction gamma-3 protein

NCBI Organism

Homo sapiens

Background Reference 01

Yang, J.J., et al. Hum. Genet. 128 (3) :303-313 (2010)

Background Reference 02

Ramchander, P.V., et al. Genet Test Mol Biomarkers 14 (4) :539-541 (2010)

Background Reference 03

Hong, H.M., et al. Hum. Genet. 127 (2) :191-199 (2010)

Background Reference 04

Wang, W.H., et al. Audiol. Neurootol. 15 (2) :81-87 (2010)

Other Product Names

Gap junction gamma-3 protein, Connexin-302, Cx302, Connexin-313, Cx313, Gap junction epsilon-1 protein, GJC3, GJE1

Tested Applications

WB

Protein ID

32171365

Physical Properties

Liquid

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