ZCCHC12 Antibody

Product Specifications

Background

Transcriptional coactivator in the bone morphogenetic protein (BMP) -signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity) .

NCBI Gene ID

170261

Swiss Prot

Q6PEW1

Accession Number

Q6PEW1

Host

Rabbit

Reactivity

Human

Immunogen

This ZCCHC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ZCCHC12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ZCCHC12

NCBI Official Name

Zinc finger CCHC domain-containing protein 12

NCBI Organism

Homo sapiens

Background Reference 01

Cho, G., et al. J. Biol. Chem. 284 (29) :19592-19600 (2009)

Background Reference 02

Li, H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41 (7) :535-544 (2009)

Background Reference 03

Cho, G., et al. Am. J. Med. Genet.146A (20), 2644-2650 (2008) :

Background Reference 04

Cho, G., et al. Mol. Cell. Biol. 28 (5) :1565-1572 (2008)

Other Product Names

Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1, ZCCHC12, SIZN1

Tested Applications

Protein ID

85718626

Physical Properties

Liquid

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