MUM1 Antibody
Product Specifications
Background
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
NCBI Gene ID
84939
Swiss Prot
Q2TAK8
Accession Number
Q2TAK8
Host
Rabbit
Reactivity
Human
Immunogen
This MUM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-699 amino acids from the C-terminal region of human MUM1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MUM1
NCBI Official Name
PWWP domain-containing protein MUM1
NCBI Organism
Homo sapiens
Background Reference 01
Huen, M.S., et al. Mol. Cell 37 (6) :854-864 (2010)
Background Reference 02
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Background Reference 03
Coulie, P.G., et al. Proc. Natl. Acad. Sci. U.S.A. 92 (17) :7976-7980 (1995)
Other Product Names
PWWP domain-containing protein MUM1, Mutated melanoma-associated antigen 1, MUM-1, Protein expandere, MUM1, EXPAND1
Tested Applications
WB
Protein ID
259016340
Physical Properties
Liquid
Curated Selection
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