UPK3B Antibody
Product Specifications
Background
UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]) .[supplied by OMIM].
NCBI Gene ID
80761
Swiss Prot
Q9BT76
Accession Number
Q9BT76
Host
Rabbit
Reactivity
Human
Immunogen
This UPK3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human UPK3B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UPK3B
NCBI Official Name
Uroplakin-3b
NCBI Organism
Homo sapiens
Background Reference 01
Foot, N.J., et al. Blood 112 (10) :4268-4275 (2008)
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Garcia-Espana, A., et al. Mol. Phylogenet. Evol. 41 (2) :355-367 (2006)
Background Reference 04
Deng, F.M., et al. J. Cell Biol. 159 (4) :685-694 (2002)
Other Product Names
Uroplakin-3b, UP3b, Uroplakin IIIb, UPIIIb, p35, UPK3B
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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