TBC1D10B Antibody
Product Specifications
Background
Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs) . TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]) .
NCBI Gene ID
26000
Swiss Prot
Q4KMP7
Accession Number
Q4KMP7
Host
Rabbit
Reactivity
Human
Immunogen
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-373
Calculated Molecular Weight
87 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TBC1D10B
NCBI Official Name
TBC1 domain family member 10B
NCBI Organism
Homo sapiens
Background Reference 01
Ishibashi, K., et al. Genes Cells 14 (1) :41-52 (2009)
Background Reference 02
Choy, K.W., et al. Physiol. Genomics 25 (1) :9-15 (2006)
Background Reference 03
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)
Other Product Names
TBC1 domain family member 10B, Rab27A-GAP-beta, TBC1D10B
Tested Applications
WB
Protein ID
294862492
Physical Properties
Liquid
Curated Selection
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