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TBC1D10B Antibody

Product Specifications

Background

Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs) . TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]) .

NCBI Gene ID

26000

Swiss Prot

Q4KMP7

Accession Number

Q4KMP7

Host

Rabbit

Reactivity

Human

Immunogen

This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

87 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TBC1D10B

NCBI Official Name

TBC1 domain family member 10B

NCBI Organism

Homo sapiens

Background Reference 01

Ishibashi, K., et al. Genes Cells 14 (1) :41-52 (2009)

Background Reference 02

Choy, K.W., et al. Physiol. Genomics 25 (1) :9-15 (2006)

Background Reference 03

Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

Other Product Names

TBC1 domain family member 10B, Rab27A-GAP-beta, TBC1D10B

Tested Applications

WB

Protein ID

294862492

Physical Properties

Liquid

Frequently Asked Questions

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