DNAJC5 Antibody

Product Specifications

Background

This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.

NCBI Gene ID

80331

Swiss Prot

Q9H3Z4

Accession Number

Q9H3Z4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DNAJC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the Central region of human DNAJC5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DNAJC5

NCBI Official Name

DnaJ homolog subfamily C member 5

NCBI Organism

Homo sapiens

Background Reference 01

Johnson, J.N., et al. Biochem. Cell Biol. 88 (2) :157-165 (2010)

Background Reference 02

Schmidt, B.Z., et al. J. Biol. Chem. 284 (7) :4168-4178 (2009)

Background Reference 03

Greaves, J., et al. J. Biol. Chem. 283 (36) :25014-25026 (2008)

Background Reference 04

Park, J., et al. Am. J. Respir. Cell Mol. Biol. 39 (1) :68-76 (2008)

Other Product Names

DnaJ homolog subfamily C member 5, Cysteine string protein, CSP, DNAJC5, CSP

Tested Applications

Protein ID

15213953

Physical Properties

Liquid

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