DACH1 Antibody
Product Specifications
Background
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
1602
Swiss Prot
Q9UI36
Accession Number
Q9UI36
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This DACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human DACH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DACH1
NCBI Official Name
Dachshund homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Kottgen, A., et al. Nat. Genet. 42 (5) :376-384 (2010)
Background Reference 04
Zhou, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (15) :6864-6869 (2010)
Other Product Names
Dachshund homolog 1, Dach1, DACH1, DACH
Tested Applications
WB
Protein ID
519668677
Physical Properties
Liquid
Frequently Asked Questions
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