DACH1 Antibody

Product Specifications

Background

This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

1602

Swiss Prot

Q9UI36

Accession Number

Q9UI36

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human DACH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

79 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DACH1

NCBI Official Name

Dachshund homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Kottgen, A., et al. Nat. Genet. 42 (5) :376-384 (2010)

Background Reference 04

Zhou, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (15) :6864-6869 (2010)

Other Product Names

Dachshund homolog 1, Dach1, DACH1, DACH

Tested Applications

Protein ID

519668677

Physical Properties

Liquid

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