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INF2 Antibody

Product Specifications

Background

This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

NCBI Gene ID

64423

Swiss Prot

Q27J81

Accession Number

Q27J81

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This INF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human INF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

136 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

INF2

NCBI Official Name

Inverted formin-2

NCBI Organism

Homo sapiens

Background Reference 01

Brown, E.J., et al. Nat. Genet. 42 (1) :72-76 (2010)

Background Reference 02

Chhabra, E.S., et al. J. Biol. Chem. 281 (36) :26754-26767 (2006)

Background Reference 03

Bindschadler, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (41) :14685-14686 (2004)

Other Product Names

Inverted formin-2, HBEBP2-binding protein C, INF2, C14orf151, C14orf173

Tested Applications

WB

Protein ID

166215588

Physical Properties

Liquid

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