INF2 Antibody
Product Specifications
Background
This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.
NCBI Gene ID
64423
Swiss Prot
Q27J81
Accession Number
Q27J81
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This INF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human INF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
136 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
INF2
NCBI Official Name
Inverted formin-2
NCBI Organism
Homo sapiens
Background Reference 01
Brown, E.J., et al. Nat. Genet. 42 (1) :72-76 (2010)
Background Reference 02
Chhabra, E.S., et al. J. Biol. Chem. 281 (36) :26754-26767 (2006)
Background Reference 03
Bindschadler, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (41) :14685-14686 (2004)
Other Product Names
Inverted formin-2, HBEBP2-binding protein C, INF2, C14orf151, C14orf173
Tested Applications
WB
Protein ID
166215588
Physical Properties
Liquid
Curated Selection
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