GTF2A1 Antibody
Product Specifications
Background
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]) . One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.
NCBI Gene ID
2957
Swiss Prot
P52655
Accession Number
P52655
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GTF2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the C-terminal region of human GTF2A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GTF2A1
NCBI Official Name
Transcription initiation factor IIA subunit 1
NCBI Organism
Homo sapiens
Background Reference 01
Huang, Y.W., et al. Oncol. Rep. 22 (4) :853-861 (2009)
Background Reference 02
Vega, A., et al. Gynecol. Oncol. 112 (1) :210-214 (2009)
Background Reference 03
Hieb, A.R., et al. J. Mol. Biol. 372 (3) :619-632 (2007)
Background Reference 04
Lee, K.A., et al. Cytokine 38 (2) :96-100 (2007)
Other Product Names
Transcription initiation factor IIA subunit 1, General transcription factor IIA subunit 1, TFIIAL, Transcription initiation factor TFIIA 42 kDa subunit, TFIIA-42, Transcription initiation factor IIA alpha chain, TFIIA p35 subunit, Transcription initiation factor IIA beta chain, TFIIA p19 subunit, GTF2A1, TF2A1
Tested Applications
WB
Protein ID
1711663
Physical Properties
Liquid
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