SNTB1 Antibody

Product Specifications

Background

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

NCBI Gene ID

6641

Swiss Prot

Q13884

Accession Number

Q13884

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SNTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human SNTB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SNTB1

NCBI Official Name

Beta-1-syntrophin

NCBI Organism

Homo sapiens

Background Reference 01

Rothenberg, M.E., et al. Nat. Genet. 42 (4) :289-291 (2010)

Background Reference 02

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Background Reference 03

Chen, Z., et al. J. Biol. Chem. 281 (18) :12414-12420 (2006)

Background Reference 04

Ejtehadi, H.D., et al. Ann. Rheum. Dis. 65 (5) :612-616 (2006)

Other Product Names

Beta-1-syntrophin, 59 kDa dystrophin-associated protein A1 basic component 1, DAPA1B, BSYN2, Syntrophin-2, Tax interaction protein 43, TIP-43, SNTB1, SNT2B1