KCNJ12 Antibody
Product Specifications
Background
This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1) . The gene is located within the Smith-Magenis syndrome region on chromosome 17.
NCBI Gene ID
3768
Swiss Prot
Q14500
Accession Number
Q14500
Host
Rabbit
Reactivity
Human
Immunogen
This KCNJ12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human KCNJ12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNJ12
NCBI Official Name
ATP-sensitive inward rectifier potassium channel 12
NCBI Organism
Homo sapiens
Background Reference 01
Collins, A., et al. J. Cell. Physiol. 219 (1) :8-13 (2009)
Background Reference 02
Ji, W., et al. Nat. Genet. 40 (5) :592-599 (2008)
Background Reference 03
Panama, B.K., et al. J. Physiol. (Lond.) 571 (PT 2), 287-302 (2006) :
Background Reference 04
Kiesecker, C., et al. J. Mol. Med. 84 (1) :46-56 (2006)
Other Product Names
ATP-sensitive inward rectifier potassium channel 12, Inward rectifier K (+) channel Kir22, IRK-2, Inward rectifier K (+) channel Kir22v, Potassium channel, inwardly rectifying subfamily J member 12, KCNJ12, IRK2, KCNJN1
Tested Applications
WB
Protein ID
77416868
Physical Properties
Liquid
Frequently Asked Questions
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