KCNJ12 Antibody

Product Specifications

Background

This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1) . The gene is located within the Smith-Magenis syndrome region on chromosome 17.

NCBI Gene ID

3768

Swiss Prot

Q14500

Accession Number

Q14500

Host

Rabbit

Reactivity

Human

Immunogen

This KCNJ12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human KCNJ12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KCNJ12

NCBI Official Name

ATP-sensitive inward rectifier potassium channel 12

NCBI Organism

Homo sapiens

Background Reference 01

Collins, A., et al. J. Cell. Physiol. 219 (1) :8-13 (2009)

Background Reference 02

Ji, W., et al. Nat. Genet. 40 (5) :592-599 (2008)

Background Reference 03

Panama, B.K., et al. J. Physiol. (Lond.) 571 (PT 2), 287-302 (2006) :

Background Reference 04

Kiesecker, C., et al. J. Mol. Med. 84 (1) :46-56 (2006)

Other Product Names

ATP-sensitive inward rectifier potassium channel 12, Inward rectifier K (+) channel Kir22, IRK-2, Inward rectifier K (+) channel Kir22v, Potassium channel, inwardly rectifying subfamily J member 12, KCNJ12, IRK2, KCNJN1