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SCO2 Antibody

Product Specifications

Background

Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy.

NCBI Gene ID

9997

Swiss Prot

O43819

Accession Number

O43819

Host

Rabbit

Reactivity

Human

Immunogen

This SCO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human SCO2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

30 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SCO2

NCBI Official Name

Protein SCO2 homolog, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Foltopoulou, P.F., et al. Biochim. Biophys. Acta 1802 (6) :497-508 (2010)

Background Reference 03

Pronicki, M., et al. Eur. J. Paediatr. Neurol. 14 (3) :253-260 (2010)

Background Reference 04

Kamatani, Y., et al. Nat. Genet. 42 (3) :210-215 (2010)

Other Product Names

Protein SCO2 homolog, mitochondrial, SCO2

Tested Applications

WB

Physical Properties

Liquid

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