AIDA Antibody
Product Specifications
Background
AIDA acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity) .
NCBI Gene ID
64853
Swiss Prot
Q96BJ3
Accession Number
Q96BJ3
Host
Rabbit
Reactivity
Human
Immunogen
This AIDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-283 amino acids from the C-terminal region of human AIDA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AIDA
NCBI Official Name
Axin interactor, dorsalization-associated protein
NCBI Organism
Homo sapiens
Background Reference 01
Rui, Y., et al. Dev. Cell 13 (2) :268-282 (2007)
Other Product Names
Axin interactor, dorsalization-associated protein, Axin interaction partner and dorsalization antagonist, AIDA, C1orf80
Tested Applications
WB
Protein ID
74751770
Physical Properties
Liquid
Curated Selection
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