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RPIA Antibody

Product Specifications

Background

The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.

NCBI Gene ID

22934

Swiss Prot

P49247

Accession Number

P49247

Host

Rabbit

Reactivity

Human

Immunogen

This RPIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-207 amino acids from the Central region of human RPIA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Pig, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-319

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RPIA

NCBI Official Name

Ribose-5-phosphate isomerase

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Berry, G.T. J. Inherit. Metab. Dis. 31 (6), 661 (2008) :

Other Product Names

Ribose-5-phosphate isomerase, Phosphoriboisomerase, RPIA, RPI

Tested Applications

WB

Protein ID

156637353

Physical Properties

Liquid

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