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RELT Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1) . This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

NCBI Gene ID

84957

Swiss Prot

Q969Z4

Accession Number

Q969Z4

Host

Rabbit

Reactivity

Human

Immunogen

This RELT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-413 amino acids from the C-terminal region of human RELT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RELT

NCBI Official Name

Tumor necrosis factor receptor superfamily member 19L

NCBI Organism

Homo sapiens

Background Reference 01

Cusick, J.K., et al. Cell. Immunol. 261 (1) :1-8 (2010)

Background Reference 02

Polek, T.C., et al. Biochem. Biophys. Res. Commun. 349 (3) :1016-1024 (2006)

Background Reference 03

Bossen, C., et al. J. Biol. Chem. 281 (20) :13964-13971 (2006)

Background Reference 04

Cusick, J.K., et al. Biochem. Biophys. Res. Commun. 340 (2) :535-543 (2006)

Other Product Names

Tumor necrosis factor receptor superfamily member 19L, Receptor expressed in lymphoid tissues, RELT, TNFRSF19L

Tested Applications

WB

Protein ID

21264092

Physical Properties

Liquid

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