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QTRT1 Antibody

Product Specifications

Background

TRNA-guanine transglycosylase (TGT; EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14; MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]) .

NCBI Gene ID

81890

Swiss Prot

Q9BXR0

Accession Number

Q9BXR0

Host

Rabbit

Reactivity

Human

Immunogen

This QTRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-371 amino acids from the C-terminal region of human QTRT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-309

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

QTRT1

NCBI Official Name

Queuine tRNA-ribosyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Chen, Y.C., et al. RNA 16 (5) :958-968 (2010)

Background Reference 02

Deshpande, K.L., et al. Gene 265 (1-2), 205-212 (2001) :

Other Product Names

Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase, QTRT1, TGT, TGUT

Tested Applications

WB

Protein ID

239938842

Physical Properties

Liquid

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