QTRT1 Antibody
Product Specifications
Background
TRNA-guanine transglycosylase (TGT; EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14; MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]) .
NCBI Gene ID
81890
Swiss Prot
Q9BXR0
Accession Number
Q9BXR0
Host
Rabbit
Reactivity
Human
Immunogen
This QTRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-371 amino acids from the C-terminal region of human QTRT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
QTRT1
NCBI Official Name
Queuine tRNA-ribosyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Chen, Y.C., et al. RNA 16 (5) :958-968 (2010)
Background Reference 02
Deshpande, K.L., et al. Gene 265 (1-2), 205-212 (2001) :
Other Product Names
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase, QTRT1, TGT, TGUT
Tested Applications
WB
Protein ID
239938842
Physical Properties
Liquid
Curated Selection
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