TTDN1 Antibody

Product Specifications

Background

The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.

NCBI Gene ID

136647

Swiss Prot

Q8TAP9

Accession Number

Q8TAP9

Host

Rabbit

Reactivity

Human

Immunogen

This TTDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the C-terminal region of human TTDN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MPLKIP

NCBI Official Name

M-phase-specific PLK1-interacting protein

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, Y., et al. Cell. Mol. Life Sci. 64 (5) :632-640 (2007)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Botta, E., et al. Hum. Mutat. 28 (1) :92-96 (2007)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

M-phase-specific PLK1-interacting protein, TTD non-photosensitive 1 protein, MPLKIP, C7orf11, TTDN1

Tested Applications

Protein ID

71153365

Physical Properties

Liquid

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