TPM2 Antibody

Product Specifications

Background

This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7169

Swiss Prot

P07951

Accession Number

P07951

Host

Rabbit

Reactivity

Human

Immunogen

This TPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the C-terminal region of human TPM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TPM2

NCBI Official Name

Tropomyosin beta chain

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Martins-de-Souza, D., et al.Psychiatr Res 44 (14) :989-991 (2010)

Background Reference 03

Assinder, S.J., et al. Mol. Carcinog. 49 (6) :525-531 (2010)

Background Reference 04

Ochala, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (21) :9807-9812 (2010)

Other Product Names

Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2, TPM2, TMSB

Tested Applications

Protein ID

136090

Physical Properties

Liquid

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