TYRP1 Antibody

Product Specifications

Background

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

NCBI Gene ID

7306

Swiss Prot

P17643

Accession Number

P17643

Host

Rabbit

Reactivity

Human

Immunogen

This TYRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-371 amino acids from the Central region of human TYRP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TYRP1

NCBI Official Name

5,6-dihydroxyindole-2-carboxylic acid oxidase

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Rausch, M.P., et al. J. Immunol. 185 (5) :2828-2835 (2010)

Background Reference 03

Eriksson, N., et al. PLoS Genet. (6), E1000993 (2010) :

Background Reference 04

Edwards, M., et al. PLoS Genet. (3), E1000867 (2010) :

Other Product Names

6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, 11418-, Catalase B, Glycoprotein 75, Melanoma antigen gp75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1, TYRP1, CAS2, TYRP, TYRRP