TGM3 Antibody
Product Specifications
Background
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
NCBI Gene ID
7053
Swiss Prot
Q08188
Accession Number
Q08188
Host
Rabbit
Reactivity
Human
Immunogen
This TGM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-567 amino acids from the C-terminal region of human TGM3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-272
Calculated Molecular Weight
77 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TGM3
NCBI Official Name
Protein-glutamine gamma-glutamyltransferase E
NCBI Organism
Homo sapiens
Background Reference 01
Yamane, A., et al. FEBS J. 277 (17) :3564-3574 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Negishi, A., et al. Cancer Sci. 100 (9) :1605-1611 (2009)
Background Reference 04
Fujimoto, A., et al. J. Hum. Genet. 54 (8) :461-465 (2009)
Other Product Names
Protein-glutamine gamma-glutamyltransferase E, Transglutaminase E, TG (E), TGE, TGase E, Transglutaminase-3, TGase-3, Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain, Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain, TGM3
Tested Applications
WB
Protein ID
257051080
Physical Properties
Liquid
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