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UBE2Q1 Antibody

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.

NCBI Gene ID

55585

Swiss Prot

Q7Z7E8

Accession Number

Q7Z7E8

Host

Rabbit

Reactivity

Human

Immunogen

This UBE2Q1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-104 amino acids from the N-terminal region of human UBE2Q1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UBE2Q1

NCBI Official Name

Ubiquitin-conjugating enzyme E2 Q1

NCBI Organism

Homo sapiens

Background Reference 01

Wassler, M.J., et al. Stem Cells 26 (8) :2006-2018 (2008)

Background Reference 02

Grelle, G., et al. Mol. Cell Proteomics 5 (2) :234-244 (2006)

Background Reference 03

Wistow, G., et al. Mol. Vis. 8, 205-220 (2002) :

Background Reference 04

Marenholz, I., et al. Genome Res. 11 (3) :341-355 (2001)

Other Product Names

Ubiquitin-conjugating enzyme E2 Q1, Protein NICE-5, Ubiquitin carrier protein Q1, Ubiquitin-protein ligase Q1, UBE2Q1, NICE5, UBE2Q

Tested Applications

WB

Protein ID

74750234

Physical Properties

Liquid

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