NOXO1 Antibody
Product Specifications
Background
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS) . NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]) .
NCBI Gene ID
124056
Swiss Prot
Q8NFA2
Accession Number
Q8NFA2
Host
Rabbit
Reactivity
Human
Immunogen
This NOXO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human NOXO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=59-241
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NOXO1
NCBI Official Name
NADPH oxidase organizer 1
NCBI Organism
Homo sapiens
Background Reference 01
Dutta, S., et al. PLoS ONE (5), E10478 (2010) :
Background Reference 02
Opitz, N., et al. Free Radic. Biol. Med. 42 (2) :175-179 (2007)
Background Reference 03
Yamamoto, A., et al. Biochem. Biophys. Res. Commun. 352 (2) :560-565 (2007)
Background Reference 04
Takeya, R., et al. FEBS J. 273 (16) :3663-3677 (2006)
Other Product Names
NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5
Tested Applications
WB
Protein ID
74751269
Physical Properties
Liquid
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