NOXO1 Antibody

Product Specifications

Background

NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS) . NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]) .

NCBI Gene ID

124056

Swiss Prot

Q8NFA2

Accession Number

Q8NFA2

Host

Rabbit

Reactivity

Human

Immunogen

This NOXO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human NOXO1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NOXO1

NCBI Official Name

NADPH oxidase organizer 1

NCBI Organism

Homo sapiens

Background Reference 01

Dutta, S., et al. PLoS ONE (5), E10478 (2010) :

Background Reference 02

Opitz, N., et al. Free Radic. Biol. Med. 42 (2) :175-179 (2007)

Background Reference 03

Yamamoto, A., et al. Biochem. Biophys. Res. Commun. 352 (2) :560-565 (2007)

Background Reference 04

Takeya, R., et al. FEBS J. 273 (16) :3663-3677 (2006)

Other Product Names

NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5