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CACNB3 Antibody

Product Specifications

Background

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

NCBI Gene ID

784

Swiss Prot

P54284

Accession Number

P54284

Host

Rabbit

Reactivity

Human

Immunogen

This CACNB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-434 amino acids from the C-terminal region of human CACNB3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CACNB3

NCBI Official Name

Voltage-dependent L-type calcium channel subunit beta-3

NCBI Organism

Homo sapiens

Background Reference 01

Zhang, Y., et al. J. Biol. Chem. 285 (4) :2527-2536 (2010)

Background Reference 02

Bernardo, J.F., et al. Can. J. Physiol. Pharmacol. 87 (7) :522-530 (2009)

Background Reference 03

Voss, M., et al. BMC Immunol. 10, 53 (2009) :

Background Reference 04

Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

Other Product Names

Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3, CACNB3, CACNLB3

Tested Applications

WB

Protein ID

1705683

Physical Properties

Liquid

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