MTRF1 Antibody

Product Specifications

Background

The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq].

NCBI Gene ID

9617

Swiss Prot

O75570

Accession Number

O75570

Host

Rabbit

Reactivity

Human

Immunogen

This MTRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the Central region of human MTRF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MTRF1

NCBI Official Name

Peptide chain release factor 1, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Antonicka, H., et al. Am. J. Hum. Genet. 87 (1) :115-122 (2010)

Background Reference 02

Nozaki, Y., et al. Genes Cells 13 (5) :429-438 (2008)

Background Reference 03

Soleimanpour-Lichaei, H.R., et al. Mol. Cell 27 (5) :745-757 (2007)

Background Reference 04

Hansen, L.L., et al. Cytogenet. Cell Genet. 88 (1-2), 91-92 (2000) :

Other Product Names

Peptide chain release factor 1, mitochondrial, MRF-1, MtRF-1, MTRF1

Tested Applications

Physical Properties

Liquid

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