SPIRE1 Antibody

Product Specifications

Background

Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]) .[supplied by OMIM].

NCBI Gene ID

56907

Swiss Prot

Q08AE8

Accession Number

Q08AE8

Host

Rabbit

Reactivity

Human

Immunogen

This SPIRE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-691 amino acids from the C-terminal region of human SPIRE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

86 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SPIRE1

NCBI Official Name

Protein spire homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Pechlivanis, M., et al. J. Biol. Chem. 284 (37) :25324-25333 (2009)

Background Reference 03

Bosch, M., et al. Mol. Cell 28 (4) :555-568 (2007)

Background Reference 04

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Other Product Names

Protein spire homolog 1, Spir-1, SPIRE1 {ECO:0000312|EMBL:AAI252071}, KIAA1135, SPIR1

Tested Applications

Protein ID

425906061

Physical Properties

Liquid

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