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AMICA1 Antibody

Product Specifications

Background

AMICA1 may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.

NCBI Gene ID

120425

Swiss Prot

Q86YT9

Accession Number

Q86YT9

Host

Rabbit

Reactivity

Human

Immunogen

This AMICA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the N-terminal region of human AMICA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AMICA1

NCBI Official Name

Junctional adhesion molecule-like

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Luissint, A.C., et al. J. Cell Biol. 183 (6) :1159-1173 (2008)

Background Reference 03

Zen, K., et al. Mol. Biol. Cell 16 (6) :2694-2703 (2005)

Background Reference 04

Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)

Other Product Names

Junctional adhesion molecule-like, Adhesion molecule interacting with CXADR antigen 1, Dendritic cell-specific protein CREA7-1, AMICA1, JAML

Tested Applications

WB

Protein ID

71151910

Physical Properties

Liquid

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