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ARID5B Antibody

Product Specifications

Background

DNA-binding protein that binds to the 5'-AATA[CT]-3' core sequence. Probably acts as a transcription regulator. Represses the cytomegalovirus enhancer. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may act as a regulator of smooth muscle cell differentiation and proliferation. May be involved in lipid stores.

NCBI Gene ID

84159

Swiss Prot

Q14865

Accession Number

Q14865

Host

Rabbit

Reactivity

Human

Immunogen

This ARID5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human ARID5B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

132 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARID5B

NCBI Official Name

AT-rich interactive domain-containing protein 5B

NCBI Organism

Homo sapiens

Background Reference 01

Healy, J., et al. Haematologica 95 (9) :1608-1611 (2010)

Background Reference 02

Yang, W., et al. Leukemia 24 (4) :894-896 (2010)

Background Reference 03

Prasad, R.B., et al. Blood 115 (9) :1765-1767 (2010)

Background Reference 04

Papaemmanuil, E., et al. Nat. Genet. 41 (9) :1006-1010 (2009)

Other Product Names

AT-rich interactive domain-containing protein 5B, ARID domain-containing protein 5B, MRF1-like protein, Modulator recognition factor 2, MRF-2, ARID5B, DESRT, MRF2

Tested Applications

WB

Protein ID

209572763

Physical Properties

Liquid

Frequently Asked Questions

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