PRIM2 Antibody

Product Specifications

Background

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit. [provided by RefSeq].

NCBI Gene ID

5558

Swiss Prot

P49643

Accession Number

P49643

Host

Rabbit

Reactivity

Human

Immunogen

This PRIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-345 amino acids from the Central region of human PRIM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRIM2

NCBI Official Name

DNA primase large subunit

NCBI Organism

Homo sapiens

Background Reference 01

Vaithiyalingam, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (31) :13684-13689 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Weiner, B.E., et al. J. Biol. Chem. 282 (46) :33444-33451 (2007)

Background Reference 04

Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

Other Product Names

DNA primase large subunit, 277-, DNA primase 58 kDa subunit, p58, PRIM2, PRIM2A

Tested Applications

Protein ID

51338777

Physical Properties

Liquid

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