MLF1IP Antibody

Product Specifications

Background

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) . MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]) .

NCBI Gene ID

79682

Swiss Prot

Q71F23

Accession Number

Q71F23

Host

Rabbit

Reactivity

Human

Immunogen

This MLF1IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human MLF1IP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CENPU

NCBI Official Name

Centromere protein U

NCBI Organism

Homo sapiens

Background Reference 01

Suzuki, H., et al. Anticancer Res. 27 (3B), 1423-1430 (2007) :

Background Reference 02

Kang, Y.H., et al. Mol. Cell 24 (3) :409-422 (2006)

Background Reference 03

Izuta, H., et al. Genes Cells 11 (6) :673-684 (2006)

Background Reference 04

Okada, M., et al. Nat. Cell Biol. 8 (5) :446-457 (2006)

Other Product Names

Centromere protein U, CENP-U, Centromere protein of 50 kDa, CENP-50, Interphase centromere complex protein 24, KSHV latent nuclear antigen-interacting protein 1, MLF1-interacting protein, Polo-box-interacting protein 1, CENPU, ICEN24, KLIP1, MLF1IP, PBIP1