AP2S1 Antibody
Product Specifications
Background
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.
NCBI Gene ID
1175
Swiss Prot
P53680
Accession Number
P53680
Host
Rabbit
Reactivity
Human
Immunogen
This AP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human AP2S1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AP2S1
NCBI Official Name
AP-2 complex subunit sigma
NCBI Organism
Homo sapiens
Background Reference 01
Stove, V., et al. J. Virol. 79 (17) :11422-11433 (2005)
Background Reference 02
Lu, W., et al. Neuron 47 (3) :407-421 (2005)
Background Reference 03
Collins, B.M., et al. Cell 109 (4) :523-535 (2002)
Background Reference 04
Yano, H., et al. J. Neurosci. 21 (3), RC125 (2001) :
Other Product Names
AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, HA2 17 kDa subunit, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, AP2S1, AP17, CLAPS2
Tested Applications
WB
Protein ID
51338780
Physical Properties
Liquid
Frequently Asked Questions
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