AP2S1 Antibody

Product Specifications

Background

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.

NCBI Gene ID

1175

Swiss Prot

P53680

Accession Number

P53680

Host

Rabbit

Reactivity

Human

Immunogen

This AP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human AP2S1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AP2S1

NCBI Official Name

AP-2 complex subunit sigma

NCBI Organism

Homo sapiens

Background Reference 01

Stove, V., et al. J. Virol. 79 (17) :11422-11433 (2005)

Background Reference 02

Lu, W., et al. Neuron 47 (3) :407-421 (2005)

Background Reference 03

Collins, B.M., et al. Cell 109 (4) :523-535 (2002)

Background Reference 04

Yano, H., et al. J. Neurosci. 21 (3), RC125 (2001) :

Other Product Names

AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, HA2 17 kDa subunit, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, AP2S1, AP17, CLAPS2