HLF Antibody
Product Specifications
Background
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
NCBI Gene ID
3131
Swiss Prot
Q16534
Accession Number
Q16534
Host
Rabbit
Reactivity
Human
Immunogen
This HLF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human HLF.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
HLF
NCBI Official Name
Hepatic leukemia factor
NCBI Organism
Homo sapiens
Background Reference 01
Hirose, K., et al. Blood 116 (6) :962-970 (2010)
Background Reference 02
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)
Background Reference 03
Otto, T., et al. Endocrinology 149 (5) :2241-2250 (2008)
Background Reference 04
Inukai, T., et al. Leukemia 21 (2) :288-296 (2007)
Other Product Names
Hepatic leukemia factor, HLF
Tested Applications
WB
Protein ID
6919907
Physical Properties
Liquid
Curated Selection
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