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HLF Antibody

Product Specifications

Background

This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

NCBI Gene ID

3131

Swiss Prot

Q16534

Accession Number

Q16534

Host

Rabbit

Reactivity

Human

Immunogen

This HLF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human HLF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

33 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

HLF

NCBI Official Name

Hepatic leukemia factor

NCBI Organism

Homo sapiens

Background Reference 01

Hirose, K., et al. Blood 116 (6) :962-970 (2010)

Background Reference 02

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)

Background Reference 03

Otto, T., et al. Endocrinology 149 (5) :2241-2250 (2008)

Background Reference 04

Inukai, T., et al. Leukemia 21 (2) :288-296 (2007)

Other Product Names

Hepatic leukemia factor, HLF

Tested Applications

WB

Protein ID

6919907

Physical Properties

Liquid

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