ARL6IP5 Antibody

Product Specifications

Background

Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.

NCBI Gene ID

10550

Swiss Prot

O75915

Accession Number

O75915

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ARL6IP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the Central region of human ARL6IP5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARL6IP5

NCBI Official Name

PRA1 family protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34 (5) :840-852 (2010)

Background Reference 02

Akiduki, S., et al. J. Biol. Chem. 283 (46) :31323-31332 (2008)

Background Reference 03

Ruggiero, A.M., et al. J. Biol. Chem. 283 (10) :6175-6183 (2008)

Background Reference 04

Watabe, M., et al. Mol. Pharmacol. 72 (5) :1103-1110 (2007)

Other Product Names

PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, JM5, Prenylated Rab acceptor protein 2, Protein JWa, Putative MAPK-activating protein PM27, ARL6IP5, DERP11, JWA, PRA2, PRAF3