PAFAH2 Antibody

Product Specifications

Background

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) . However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.

NCBI Gene ID

5051

Swiss Prot

Q99487

Accession Number

Q99487

Host

Rabbit

Reactivity

Human

Immunogen

This PAFAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-276 amino acids from the Central region of human PAFAH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PAFAH2

NCBI Official Name

Platelet-activating factor acetylhydrolase 2, cytoplasmic

NCBI Organism

Homo sapiens

Background Reference 01

Schmidt, E.B., et al. Atherosclerosis 196 (1) :420-424 (2008)

Background Reference 02

Umemura, K., et al. Stroke 38 (3) :1063-1068 (2007)

Background Reference 03

Unno, N., et al. J. Surg. Res. 134 (1) :36-43 (2006)

Background Reference 04

Marques, M., et al. J. Invest. Dermatol. 119 (4) :913-919 (2002)

Other Product Names

Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2, SD-PLA2, hSD-PLA2, PAFAH2

Tested Applications

Protein ID

6647691

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MR205485L1 10 µg

Cxcr4 (NM_009911) Mouse Tagged Lenti ORF Clone

Ask

View Details

DF3108-BP 1 mg

Adrenergic Receptor alpha -2C Peptide

Ask

View Details